Dencker H, Jägerstad M, Westesson A K
Acta Hepatogastroenterol (Stuttg). 1976 Apr;23(2):140-3.
Folic acid in amounts of 2 mumol (0.88 mg) was given by mouth to four patients who had undergone portal vein catheterization. All had normal liver function. The increase in folates in plasma obtained from portal and peripheral veins was followed for three hours with the use of L. casei and S. faecalis as test organisms. The results lend support to the assumption that the liver is the main site of methylation of folic acid when given in physiological amounts.
给4名接受门静脉插管的患者口服2微摩尔（0.88毫克）叶酸。所有患者肝功能均正常。以干酪乳杆菌和粪肠球菌作为测试菌，观察口服叶酸后3小时门静脉血和外周血中叶酸水平的变化。结果支持了以下假设：给予生理剂量的叶酸时，肝脏是叶酸甲基化的主要部位。
