Archibong E I, Sobande A A, Asindi A A
Department of Obstetrics and Gynaecology, Abha Maternity Hospital, Abha, Saudi Arabia.
J Obstet Gynaecol. 2003 Mar;23(2):170-3. doi: 10.1080/0144361031000074728.
This study was conducted to determine the frequency of antenatal intrauterine fetal death (IUFD) and the associated maternal and fetal risk factors in women who presented at a regional tertiary hospital in Saudi Arabia. Over a 5-year period, 191 consecutive cases of IUFD presented and were studied prospectively. Relevant maternal and fetal data were obtained. The stillbirth rate during the period was 10 per 1000 deliveries. In 41% of the cases, the associated causal factors could not be determined. There was a significant (P = 0.00122) linear trend showing an increased risk of IUFD above the age of 20 years and, similarly, a significant (P = 0.00047) linear trend after the first pregnancy. Lack of antenatal care (88.5%), hypertensive diseases in pregnancy (12%) and diabetes mellitus (8%) were associated risk factors while 'major congenital malformation' (14%) was an outstanding fetal factor. The risk factors of antenatal stillbirth in our community seem to be avoidable. Health education to encourage the utilisation of the available antenatal care services, family planning and genetic counselling are being advocated strongly as possible preventive measures.
本研究旨在确定沙特阿拉伯一家地区三级医院收治的孕妇中产前宫内胎儿死亡（IUFD）的发生率以及相关的母婴危险因素。在5年期间，前瞻性研究了连续出现的191例IUFD病例。获取了相关的母婴数据。该时期的死产率为每1000例分娩中有10例。在41%的病例中，无法确定相关的因果因素。存在显著（P = 0.00122）的线性趋势，表明20岁以上IUFD风险增加，同样，首次怀孕后也存在显著（P = 0.00047）的线性趋势。缺乏产前护理（88.5%）、妊娠高血压疾病（12%）和糖尿病（8%）是相关危险因素，而“严重先天性畸形”（14%）是一个突出的胎儿因素。我们社区产前死产的危险因素似乎是可以避免的。强烈倡导开展健康教育，鼓励利用现有的产前护理服务、计划生育和遗传咨询，将其作为可能的预防措施。
