Hallgrímsson J
Acta Pathol Microbiol Scand A. 1976 May;84(3):247-52.
The frequency of chronic non-rheumatic valvular heart disease in Iceland was investigated via autoposies performed from November 1965 through December 1974. During this period, about 12.400 Icelanders died at the age of 16 years and older and 28.8 per cent of these were included in the study. At autopsy, males outnumbered females by 2:1. The frequency of calcific aortic stenosis was found to be 3.63 per cent and the prevalence was calculated to be 3.17 per cent among males and 4.50 per cent among females. Calcific aortic stenosis in tricuspid valves was more frequent in females and calcific aortic stenosis in bicuspid valves was more frequent in males. Among the hearts with calcific aortic stenosis, 70.8 per cent were found to have normally tricuspid valves, 25.4 per cent bicuspid valves and 3.8 per cent tricuspid valves with an unicommissural fusion. In 0.59 per cent of the hearts the aortic valve was either bicuspid or had an uncommissural fusion without the features of calcific stenosis. However, a functional stenosis was suggested by the increased weight of most of these hearts. The frequency of bicuspid aortic valves was 1.2 per cent with a prevalence in males of 1.54 per cent and in females 0.50 per cent. A calcified mitral annulus was found in 1.98 per cent of the hearts and in most, it was either associated with calcific aortic stenosis in a tricuspid valve, or it was a single valvular disease. Rheumatic valvular disease was found in 1.08 per cent of the heart examined.
通过1965年11月至1974年12月期间进行的尸检，对冰岛慢性非风湿性瓣膜性心脏病的发病率进行了调查。在此期间，约12400名16岁及以上的冰岛人死亡，其中28.8%被纳入研究。尸检时，男性人数是女性的两倍。发现钙化性主动脉瓣狭窄的发病率为3.63%，男性患病率计算为3.17%，女性为4.50%。三尖瓣钙化性主动脉瓣狭窄在女性中更常见，二尖瓣钙化性主动脉瓣狭窄在男性中更常见。在有钙化性主动脉瓣狭窄的心脏中，70.8%的心脏三尖瓣正常，25.4%为二尖瓣，3.8%的三尖瓣有单联合融合。在0.59%的心脏中，主动脉瓣要么是二叶式的，要么有未联合融合但无钙化性狭窄特征。然而，这些心脏大多数重量增加提示存在功能性狭窄。二叶式主动脉瓣的发病率为1.2%，男性患病率为1.54%，女性为0.50%。在1.98%的心脏中发现有钙化的二尖瓣环，大多数情况下，它要么与三尖瓣钙化性主动脉瓣狭窄相关，要么是单一瓣膜疾病。在检查的心脏中，发现风湿性瓣膜病的比例为1.08%。
