Penther P, Boschat J, Etienne Y, Le Potier J, Gilard M
Service de cardiologie Lenègre, CHR Morvan, Brest, France.
Arch Mal Coeur Vaiss. 1988 Jul;81(7):887-93.
Anatomical data obtained from 64 patients aged from 70 to 86 years with calcified and tight aortic orifice stenosis (functional area less than 1 cm2) were divided into three types according to the macroscopic appearance of the aortic valve: (1) tricuspid valve without commissural fusion: 44 cases (18 men, 26 women, mean age 76 years); (2) tricuspid valve with commissural fusion: 12 cases (8 men, 4 women, mean age 72 years); (3) calcified congenital bicuspid valve: 8 cases (6 men, 2 women, mean age 73 years). Thus, the distribution of patients by sex became the same starting from the eighth decade of life. Calcified aortic orifice stenosis (CAOS) of degenerative origin was the most common lesion (69 p. 100), with a strong female predominance. There were several differences between degenerative CAOS and bicuspid valve stenosis on the one hand and aortic orifice stenosis with commissural fusion on the other hand. In the first group, calcification did not involve the free edge of the aortic cusps, large calcifications of the mitral ring were extremely frequent, and there was little or no aortic regurgitation. Moreover, the aortic ring clearly was wider in cases with bicuspid valve. In patients with degenerative CAOS and bicuspid valve, attempts at digital dilatation by the left ventricular route succeeded in most cases in obtaining a fairly important widening of the aortic orifice by compression and/or disruption of the valvular calcium deposits, without causing significant regurgitation of injuring the valve; the cusps recovered some mobility.(ABSTRACT TRUNCATED AT 250 WORDS)
从64例年龄在70至86岁、患有钙化且狭窄严重的主动脉瓣口狭窄(功能面积小于1平方厘米)的患者获取的解剖学数据,根据主动脉瓣的宏观外观分为三种类型:(1)无瓣叶融合的三尖瓣:44例(男性18例,女性26例,平均年龄76岁);(2)有瓣叶融合的三尖瓣:12例(男性8例,女性4例,平均年龄72岁);(3)钙化先天性二叶瓣:8例(男性6例,女性2例,平均年龄73岁)。因此,从80岁起,患者的性别分布变得相同。退行性起源的钙化主动脉瓣口狭窄(CAOS)是最常见的病变(占69%),女性占主导。退行性CAOS与二叶瓣狭窄一方面和有瓣叶融合的主动脉瓣口狭窄另一方面之间存在若干差异。在第一组中,钙化不累及主动脉瓣叶的游离缘,二尖瓣环的大钙化极为常见,且很少或没有主动脉瓣反流。此外,二叶瓣病例的主动脉环明显更宽。在患有退行性CAOS和二叶瓣的患者中,经左心室途径进行手指扩张的尝试在大多数情况下成功地通过压缩和/或破坏瓣膜钙沉积物使主动脉瓣口得到相当程度的扩大,而不会导致明显的反流或损伤瓣膜;瓣叶恢复了一些活动度。(摘要截断于250字)