Jacob M, Hunt I F, Dirige O, Swendseid M E
Am J Clin Nutr. 1976 Jun;29(6):650-6. doi: 10.1093/ajcn/29.6.650.
Biochemical parameters of nutritional status were investigated in 300 women of Mexican descent during the first and second trimesters of pregnancy. Blood samples were obtained from the women during clinic visits, and measurements were made of serum iron, hemoglobin, hematocrit, serum protein, and transferrin saturation. Additionally, the nutritional status of seven vitamins was determined either by direct assay of the vitamin levels in blood or by measurement of erythrocyte enzyme stimulation. Thiamin and riboflavin were also determined in causal urine samples. Very few women, 8% or less, were classified as being low or deficient in hemoglobin, serum protein, iron, transferrin saturation, vitamin C, carotene, vitamin A, or vitamin B12. Thirty-one percent had low or deficient hematocrit values according to the guidelines used. Folic acid was the most prevalent vitamin deficiency, with 69% of the women having low or deficient serum levels. Based on the erythrocyte enzyme stimulation tests, 22% of the women were low or deficient in thiamin, 29% were low or deficient in riboflavin, and 9% were deficient in pyridoxine. None of the women had a low urinary excretion of thiamin, but 8% had excretion values of riboflavin below the acceptable level. Fewer deficiencies of thiamin and serum folic acid were observed in women taking vitamin and mineral supplements than in those who were not.
对300名墨西哥裔女性在妊娠头三个月和第二个三个月期间的营养状况生化参数进行了调查。在门诊就诊时从这些女性身上采集血样,并对血清铁、血红蛋白、血细胞比容、血清蛋白和转铁蛋白饱和度进行测量。此外,通过直接测定血液中的维生素水平或通过测量红细胞酶刺激来确定七种维生素的营养状况。还对随意尿样中的硫胺素和核黄素进行了测定。血红蛋白、血清蛋白、铁、转铁蛋白饱和度、维生素C、胡萝卜素、维生素A或维生素B12水平低或缺乏的女性极少,占8%或更少。根据所采用的标准,31%的女性血细胞比容值低或缺乏。叶酸是最普遍缺乏的维生素,69%的女性血清水平低或缺乏。根据红细胞酶刺激试验,22%的女性硫胺素水平低或缺乏,29%的女性核黄素水平低或缺乏,9%的女性吡哆醇缺乏。没有女性硫胺素尿排泄量低,但8%的女性核黄素排泄值低于可接受水平。服用维生素和矿物质补充剂的女性中,硫胺素和血清叶酸缺乏的情况比未服用的女性少。