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[新鲜羊膜移植治疗眼表疾病]

[Fresh amniotic membrane transplantation for ocular surface diseases].

作者信息

Luo Hai-yan, Peng Shu-min, Wang Yong-jian

机构信息

Department of Ophthalmology, Second People's Hospital of Fuling District, Chongqing 408000, China.

出版信息

Di Yi Jun Yi Da Xue Xue Bao. 2003 May;23(5):488-9.

PMID:12754140
Abstract

OBJECTIVE

To evaluate the therapeutic effects of fresh amniotic membrane transplantation for ocular surface disorders (OSDs).

METHODS

Fresh amniotic membrane transplantation was performed in 38 cases (52 eyes) of ocular surface diseases, including pterygium, recurrent pterygium, Mooren's ulcer, Viral keratitis, and symblepharon. Follow-up studies ranging from 3 to 12 months were conducted.

RESULTS

No acute graft rejection was observed following the operation in these cases, and no recurrence was found in cases of pterygium and corneal ulcer during the follow-up period. The ocular movement was restored for the eyes with severe symblepharon.

CONCLUSION

Fresh amniotic membrane can be used as a graft material for ocular surface reconstruction, in which complete removal of the pathological tissues and reliable fixation of the amniotic membrane graft are crucial steps.

摘要

目的

评估新鲜羊膜移植治疗眼表疾病(OSDs)的疗效。

方法

对38例(52眼)眼表疾病患者进行新鲜羊膜移植,这些疾病包括翼状胬肉、复发性翼状胬肉、蚕蚀性角膜溃疡、病毒性角膜炎和睑球粘连。进行了3至12个月的随访研究。

结果

这些病例术后未观察到急性移植排斥反应,随访期间翼状胬肉和角膜溃疡病例未发现复发。重度睑球粘连患者的眼球运动得以恢复。

结论

新鲜羊膜可作为眼表重建的移植材料,其中彻底清除病理组织和可靠固定羊膜移植片是关键步骤。

相似文献

1
[Fresh amniotic membrane transplantation for ocular surface diseases].[新鲜羊膜移植治疗眼表疾病]
Di Yi Jun Yi Da Xue Xue Bao. 2003 May;23(5):488-9.
2
[A clinical study on fresh amniotic membrane transplantation for treatment of severe ocular surface disorders at acute inflammatory and cicatricial stage].新鲜羊膜移植治疗急性炎症期及瘢痕期重度眼表疾病的临床研究
Zhonghua Yan Ke Za Zhi. 2000 Jan;36(1):13-7, 1.
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[Amniotic membrane graft in ocular surface disease. Prospective study with 31 cases].[羊膜移植治疗眼表疾病。31例前瞻性研究]
J Fr Ophtalmol. 2001 Oct;24(8):798-812.
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[A clinical study of amniotic membrane transplantation for severe eye burns at the acute stage].[羊膜移植治疗急性期严重眼烧伤的临床研究]
Zhonghua Yan Ke Za Zhi. 2004 Feb;40(2):97-100.
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[Transplantation of amniotic membrane and amniotic membrane combined with limbal autograft for patients with complicated pterygium].羊膜移植及羊膜联合自体角膜缘移植治疗复杂性翼状胬肉
Hunan Yi Ke Da Xue Xue Bao. 2003 Apr;28(2):149-51.
6
Amniotic membrane transplantation for ocular surface reconstruction.羊膜移植用于眼表重建。
J Med Assoc Thai. 2001 May;84(5):705-18.
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Amniotic membrane transplantation in ocular surface disorders.羊膜移植在眼表疾病中的应用
J Indian Med Assoc. 2004 Dec;102(12):726-9.
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Amniotic membrane transplantation in ocular surface disorders.羊膜移植治疗眼表疾病
J Indian Med Assoc. 2005 Jul;103(7):364-6, 368.
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[Long-term results of amniotic membrane transplantation for conjunctival surface reconstruction].[羊膜移植用于结膜表面重建的长期效果]
Zhonghua Yan Ke Za Zhi. 2004 Nov;40(11):745-9.
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Effect of recombinant epidermal growth factor on ocular surface re-epithelization following amniotic membrane transplantation in patients with pterygium excision.
Di Yi Jun Yi Da Xue Xue Bao. 2002 May;22(5):437-8.

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Amniotic membrane transplantation as a new therapy for the acute ocular manifestations of Stevens-Johnson syndrome and toxic epidermal necrolysis.羊膜移植作为史蒂文斯-约翰逊综合征和中毒性表皮坏死松解症急性眼部表现的一种新疗法。
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