Sviderskaia N E, Butneva L S, Agaronov V R, Glazkova V A
Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, 17th Narcologic Hospital, Moscow. Sviderskaya@.ru
Zh Vyssh Nerv Deiat Im I P Pavlova. 2003 Mar-Apr;53(2):156-64.
Multiparametric comparative analysis of spatial organization of EEG was carried out in 137 alcoholics and 131 heroin addicts. Common and different deviations from normal EEG (105 control subjects) were found. Global alterations of EEG spatial organization were observed in drug addicts (as compared to alcoholics). Such changes characterized increasing synchronizing effects of mesolimbic and brainstem structures on the brain cortex. The ethanol effects were more specific and asymmetric. Changes in EEG spectral-coherence characteristics were revealed in all frequency band, however, maximal changes took place in the high-frequency theta in drug addicts and in narrow-frequency alpha subranges in alcoholics. Different effects on the high-frequency EEG component (19.00-21.25 Hz) and information-energy index (coherence-to-spectral power ratio) suggest the difference influence of ethanol and heroin on emotional-motivational and cognitive processes as well as the level of consciousness. The obtained data on EEG discrimination of alcoholism and drug addiction (the inverse problem solution) on the basis of "specific" EEG patterns appear to have considerable promise in development of systems of occupational selection.
对137名酗酒者和131名海洛因成瘾者进行了脑电图空间组织的多参数比较分析。发现了与正常脑电图（105名对照受试者）的共同和不同偏差。在吸毒者中观察到脑电图空间组织的整体改变（与酗酒者相比）。这些变化表现为中脑边缘和脑干结构对大脑皮层的同步作用增强。乙醇的作用更具特异性和不对称性。在所有频段都发现了脑电图频谱相干特征的变化，然而，吸毒者中高频θ频段变化最大，酗酒者中窄频α子频段变化最大。对高频脑电图成分（19.00 - 21.25赫兹）和信息能量指数（相干与频谱功率比）的不同影响表明乙醇和海洛因对情绪动机和认知过程以及意识水平有不同影响。基于“特定”脑电图模式获得的关于酗酒和吸毒的脑电图鉴别数据（逆问题解决方案）在职业选择系统的开发中似乎有很大前景。
