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[用于口服治疗和预防化脓性外科感染的大环内酯类抗生素]

[Macrolide antibiotics for oral intake in the treatment and prevention of suppurative surgical infection].

作者信息

Govorovich E A, Martshak A M, Iakovlev V P

出版信息

Antibiotiki. 1976 Apr;21(4):371-5.

PMID:1275486
Abstract

The authors studied the clinical efficacy of antibiotics of the macrolides group--erythromycin, oleandomycin, triacetylalleandomycin and leukomycin--in complex treatment of 280 patients with suppurative surgical infection caused by a gram-positive, mainly staphylococcal, microbial flora. Various medicinal forms were used: tablets, capsules, granules, syrup. Efficacy of treatment comprised 70-78 per cent. Tolerance of antibiotics was good in the majority of patients.

摘要

作者研究了大环内酯类抗生素——红霉素、竹桃霉素、三乙酰竹桃霉素和柱晶白霉素——对280例由革兰氏阳性菌(主要是葡萄球菌)微生物菌群引起的化脓性外科感染患者进行综合治疗的临床疗效。使用了各种剂型:片剂、胶囊、颗粒剂、糖浆剂。治疗有效率为70%至78%。大多数患者对抗生素耐受性良好。

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