Howarth B, Wyatt R D
Appl Environ Microbiol. 1976 May;31(5):680-4. doi: 10.1128/aem.31.5.680-684.1976.
The effects of aflatoxin on egg production, fertility, hatchability, and progeny performance were investigated by feeding dietary aflatoxin at dose levels of 0,5, and 10 mug/g to mature broiler breeder hens for 4 weeks. Sixteen hens were used for each dietary dose level. Egg production decreased significantly during weeks 3 and 4 after initiation of toxin feeding for hens fed 10 and 5 mum of aflatoxin per g of diet respectively. Whereas fertility was not affected by dietary aflatoxin, hatchability of fertile eggs decreased significantly within week 1 of toxin feeding. Hatchability of fertile eggs collected during week 1 of the treatment period was 95.1, 68.9, and 48.5% for the control, 5- and 10-mug/g groups, respectively. At the dose levels used in this study, no latent effects of the aflatoxin or its metabolites were observed on the performance of surviving chicks. Six hens from each experimental groups were necropsied at the end of the 4-week treatment period. These birds exhibited typical symptoms of aflatoxicosis, including enlarged, fatty and friable livers, and enlarged spleens.
通过给成熟的肉种母鸡饲喂剂量水平分别为0、5和10微克/克的黄曲霉毒素日粮4周，研究了黄曲霉毒素对产蛋量、受精率、孵化率和后代性能的影响。每个日粮剂量水平使用16只母鸡。分别给每克日粮饲喂10和5微克黄曲霉毒素的母鸡，在开始饲喂毒素后的第3周和第4周，产蛋量显著下降。虽然日粮黄曲霉毒素对受精率没有影响，但在饲喂毒素的第1周内，受精蛋的孵化率显著下降。在处理期第1周收集的受精蛋的孵化率，对照组、5微克/克组和10微克/克组分别为95.1%、68.9%和48.5%。在本研究使用的剂量水平下，未观察到黄曲霉毒素或其代谢产物对存活雏鸡的性能有潜在影响。在4周处理期结束时，对每个实验组的6只母鸡进行了解剖。这些鸡表现出典型的黄曲霉毒素中毒症状，包括肝脏肿大、脂肪变性和易碎，以及脾脏肿大。
