• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Objective measurement of rheumatoid arthritis using technetium index.使用锝指数对类风湿性关节炎进行客观测量。
Ann Rheum Dis. 1976 Feb;35(1):81-82. doi: 10.1136/ard.35.1.81.
2
Clinical evaluation of novel anti-rheumatic drugs.新型抗风湿药物的临床评估
Agents Actions Suppl. 1977(3):165-9. doi: 10.1007/978-3-0348-7290-4_16.
3
Penicillamine and other remittive agents in rheumatoid arthritis: comparisons and interaction.青霉胺及类风湿关节炎中的其他缓解病情药物:比较与相互作用
Clin Invest Med. 1984;7(1):59-63.
4
[Chlorbutin, azathioprine, D-penicillamine and dekaris (levamisole) in the treatment of rheumatoid arthritis. Comparative analysis of their effect on the indices of disease activity and progression].
Ter Arkh. 1982;54(6):82-92.
5
D-penicillamine-induced myositis in rheumatoid arthritis.
Clin Rheumatol. 1996 Jan;15(1):86-7. doi: 10.1007/BF02231694.
6
Therapeutic update. Clinical strategy in rheumatoid arthritis.
Singapore Med J. 1982 Dec;23(6):344-8.
7
Penicillamine for rheumatoid arthritis.
Med Lett Drugs Ther. 1978 Aug 25;20(17):73-4.
8
[Evaluation and the future of new antirheumatic drugs].[新型抗风湿药物的评估与未来]
Ter Arkh. 1978;50(9):14-6.
9
[The basic therapy of rheumatoid arthritis].[类风湿关节炎的基础治疗]
Ter Arkh. 1988;60(4):148-54.
10
Drug treatment of rheumatoid arthritis. A systematic approach.类风湿关节炎的药物治疗。一种系统的方法。
Lancet. 1975 May 24;1(7917):1176-80. doi: 10.1016/s0140-6736(75)93150-5.

引用本文的文献

1
Long-term low dose haloperidol treatment in rheumatoid patients: effects on serum sulphydryl levels, technetium index, ESR, and clinical response.类风湿患者长期低剂量氟哌啶醇治疗:对血清巯基水平、锝指数、红细胞沉降率及临床反应的影响。
Br J Clin Pharmacol. 1981 Oct;12(4):579-81. doi: 10.1111/j.1365-2125.1981.tb01268.x.
2
Non-steroidal anti-inflammatory drugs. Current status and rational therapeutic use.非甾体抗炎药。现状与合理治疗应用。
Drugs. 1984 Mar;27(3):232-55. doi: 10.2165/00003495-198427030-00004.
3
Yttrium-90 therapy and 99MTc pertechnetate knee uptake measurements in the management of rheumatoid arthritis.
Ann Rheum Dis. 1983 Apr;42(2):132-7. doi: 10.1136/ard.42.2.132.
4
Radiological evaluation of erosions: a quantitative method for assessing long-term remittive therapy in rheumatoid arthritis.糜烂的放射学评估:一种评估类风湿关节炎长期缓解治疗的定量方法。
Br J Clin Pharmacol. 1986;22 Suppl 2(Suppl 2):173S-182S. doi: 10.1111/j.1365-2125.1986.tb03001.x.
5
Scintimetric assessment of synovitis activity during treatment with disease modifying antirheumatic drugs.
Ann Rheum Dis. 1988 Dec;47(12):995-1000. doi: 10.1136/ard.47.12.995.
6
Long-term low dose ticlopidine treatment in rheumatoid arthritis: effects on serum sulphydryl levels, technetium index, erythrocyte sedimentation rate, and clinical disease activity.类风湿关节炎的长期低剂量噻氯匹定治疗:对血清巯基水平、锝指数、红细胞沉降率及临床疾病活动度的影响
Eur J Clin Pharmacol. 1985;29(2):165-8. doi: 10.1007/BF00547416.

本文引用的文献

1
Tc-99m in the study of systemic inflammatory activity in rheumatoid arthritis. A preliminary report.锝-99m在类风湿关节炎全身炎症活动研究中的应用。初步报告。
Acta Rheumatol Scand. 1971;17(1):27-30. doi: 10.3109/rhe1.1971.17.issue-1-4.04.
2
Clinical studies with an articular index for the assessment of joint tenderness in patients with rheumatoid arthritis.一项使用关节指数评估类风湿关节炎患者关节压痛情况的临床研究。
Q J Med. 1968 Jul;37(147):393-406.
3
Clinical measurement of the anti-inflammatory effects of salicylates in rheumatoid arthritis.水杨酸酯类药物在类风湿关节炎中抗炎作用的临床测量
Br Med J. 1967 Nov 4;4(5574):264-8. doi: 10.1136/bmj.4.5574.264.
4
Isotopic indices as a measure of inflammation in rheumatoid arthritis.同位素指标作为类风湿性关节炎炎症的一种衡量方式。
Ann Rheum Dis. 1974 Nov;33(6):523-5. doi: 10.1136/ard.33.6.523.

使用锝指数对类风湿性关节炎进行客观测量。

Objective measurement of rheumatoid arthritis using technetium index.

作者信息

Huskisson E C, Scott J, Balme H W

出版信息

Ann Rheum Dis. 1976 Feb;35(1):81-82. doi: 10.1136/ard.35.1.81.

DOI:10.1136/ard.35.1.81
PMID:1275586
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1006514/
Abstract

The technetium index was measured in 22 patients with rheumatoid arthritis, before and after 6 months' treatment either with penicillamine or with anti-inflammatory drugs. The index was calculated by dividing the sum of the count rates over both knees and both wrists by the dose of technetium given. In the penicillamine group there was a significant reduction in the technetium index and the changes correlated well with some clinical measurements of improvement. It is suggested that the technetium index is a useful objective measure of the effects of drugs with a specific activity in rheumatoid arthritis.

摘要

对22名类风湿性关节炎患者在使用青霉胺或抗炎药物治疗6个月前后测量了锝指数。该指数通过双膝和双腕计数率之和除以给予的锝剂量来计算。在青霉胺组中,锝指数显著降低,且这些变化与一些改善的临床测量结果密切相关。有人认为,锝指数是类风湿性关节炎中具有特定活性药物疗效的一种有用的客观测量指标。