Shaalan Wael E, French-Sherry Eileen, Castilla Maria, Lozanski Laurie, Bassiouny Hisham S
Department of Surgery, Section of Vascular Surgery, University of Chicago, IL 60637, USA.
J Vasc Surg. 2003 May;37(5):960-9. doi: 10.1067/mva.2003.282.
We investigated the utility of color duplex ultrasound (CDU)-derived common femoral artery (CFA) hemodynamics for detecting significant aortoiliac occlusive disease and predicting its severity.
From January 1997 to June 2001, 132 consecutive patients with lower extremity arterial insufficiency underwent both femoropopliteal CDU scanning and aortography with runoff studies. CDU-derived CFA waveform contour (monophasic, biphasic, or triphasic), peak systolic velocity (PSV), and acceleration time were recorded for each patient. Severity of aortoiliac occlusive disease was classified by arteriography into three distinct groups: normal or minimal disease (<50%, group 1), significant focal or diffuse stenoses (>/=50%, group 2), or total occlusion (group 3). Using probability and receiver operating characteristic curve analysis, waveform contour and PSV were compared alone and in combination with the arteriographic groups to identify waveform contours and threshold PSV, which may accurately differentiate the three categories of aortoiliac occlusive disease.
Of 214 limbs available for study, 112 composed group 1, 70 composed group 2, and 32 composed group 3. Concomitant femoropopliteal disease was present in 47% of limbs in group 1, 53% of limbs in group 2, and 34% of limbs in group III. An abnormal CFA waveform contour (monophasic or biphasic) differentiated group 1 from groups 2 and 3, with 95% sensitivity, 89% specificity, 89% positive predictive value (PPV), 95% negative predictive value (NPV), and 92% accuracy. Mean PSV and acceleration time for monophasic and biphasic waveforms were 39 cm/sec +/- 19, 178 msec +/- 36 vs 95 cm/sec +/- 67, 97 msec +/- 31 respectively (P <.05). In differentiating between groups 2 and 3, the specificity, PPV, and accuracy for CFA PSV of </=45 cm/sec alone and for the PSV </=45 cm/sec combined with a CFA monophasic waveform were 89%, 76%, 85% and 97%, 92%, 88%, respectively. Concomitant significant superior femoral artery and bilateral iliac disease did not influence these findings.
CFA PSV 45 cm/s or less combined with a monophasic waveform is highly predictive of ipsilateral iliac occlusion. These results were independent of contralateral iliac and distal superior femoral artery disease. CFA color duplex US scanning may be considered an alternative technique to direct duplex scanning of the aortoiliac segment in patients being evaluated for inflow endoluminal or bypass procedures.
我们研究了彩色双功超声(CDU)得出的股总动脉(CFA)血流动力学在检测严重主髂动脉闭塞性疾病及预测其严重程度方面的效用。
1997年1月至2001年6月,132例连续的下肢动脉供血不足患者接受了股腘动脉CDU扫描及主动脉造影和下肢动脉造影。记录每位患者CDU得出的CFA波形轮廓(单相、双相或三相)、收缩期峰值流速(PSV)和加速时间。主髂动脉闭塞性疾病严重程度通过动脉造影分为三个不同组:正常或轻度疾病(<50%,第1组)、严重局灶性或弥漫性狭窄(≥50%,第2组)或完全闭塞(第3组)。使用概率和受试者工作特征曲线分析,单独及结合动脉造影组比较波形轮廓和PSV,以确定可准确区分主髂动脉闭塞性疾病三类情况的波形轮廓和PSV阈值。
在可供研究的214条肢体中,112条属于第1组,70条属于第2组,32条属于第3组。第1组47%的肢体、第2组53%的肢体和第3组34%的肢体存在股腘动脉合并疾病。异常的CFA波形轮廓(单相或双相)可将第1组与第2组和第3组区分开,敏感性为95%,特异性为89%,阳性预测值(PPV)为89%,阴性预测值(NPV)为95%,准确性为92%。单相和双相波形的平均PSV和加速时间分别为39 cm/秒±19、178毫秒±36与95 cm/秒±67、97毫秒±31(P<.05)。在区分第2组和第3组时,单独CFA PSV≤45 cm/秒以及CFA PSV≤45 cm/秒结合CFA单相波形的特异性、PPV和准确性分别为89%、76%、85%和97%、92%、88%。股总动脉近端及双侧髂动脉合并严重疾病并不影响这些结果。
CFA PSV≤45 cm/秒并伴有单相波形高度提示同侧髂动脉闭塞。这些结果不受对侧髂动脉及股总动脉远端疾病的影响。对于接受流入道腔内或搭桥手术评估的患者,CFA彩色双功超声扫描可被视为主髂动脉段直接双功扫描的替代技术。