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评估冠状动脉旁路移植术前颈动脉狭窄和下肢周围缺血:一项非随机临床试验。

Assessment of carotid artery stenosis and lower limb peripheral ischemia before coronary artery bypass grafting operations: a non-randomized clinical trial.

机构信息

Department of Cardiothoracic Surgery, Ain Shams University, Cairo, 11355, Egypt.

Department of Anesthesiology, Ain Shams University, Cairo, Egypt.

出版信息

J Cardiothorac Surg. 2020 Sep 29;15(1):283. doi: 10.1186/s13019-020-01340-7.

DOI:10.1186/s13019-020-01340-7
PMID:32993716
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7525944/
Abstract

BACKGROUND

Atherosclerosis is a systemic disease affecting the coronary, carotid, and lower limb arteries. Cerebrovascular accidents and lower limb ischemia are devastating postoperative complications. We aimed to evaluate the role of non-selective routine arterial duplex scanning in patients undergoing coronary artery bypass grafting (CABG).

METHODS

This non-randomized clinical trial included 360 patients scheduled for elective isolated CABG who were divided into two groups: low-risk (n = 180) and high-risk (n = 180). Both groups underwent preoperative carotid and lower limb ultrasound screening for associated arteriopathy.

RESULTS

16 (8.9%) patients and 22 (12.2%) patients showed ≥70% carotid artery stenosis while 11 patients (6.1%) and 20 patients (11.1%) showed ≥50% lower limb arterial stenosis in the low-risk group and the high-risk group, respectively; though the difference was not statistically significant in both the cases (p > 0.1).

CONCLUSION

Routine preoperative peripheral arterial screening by sonography is a feasible and effective strategy to avoid unnecessary post CABG complications.

TRIAL REGISTRATION

NCT03516929 , Registered in 24 th of April 2018.

摘要

背景

动脉粥样硬化是一种全身性疾病,可影响冠状动脉、颈动脉和下肢动脉。脑血管意外和下肢缺血是术后毁灭性的并发症。我们旨在评估非选择性常规动脉双重扫描在冠状动脉旁路移植术(CABG)患者中的作用。

方法

本非随机临床试验纳入了 360 例拟行择期单纯 CABG 的患者,将其分为低危组(n=180)和高危组(n=180)。两组患者均接受术前颈动脉和下肢超声筛查,以发现相关动脉疾病。

结果

在低危组和高危组中,分别有 16 名(8.9%)和 22 名(12.2%)患者颈动脉狭窄≥70%,11 名(6.1%)和 20 名(11.1%)患者下肢动脉狭窄≥50%;但在这两种情况下,差异均无统计学意义(p>0.1)。

结论

术前常规外周动脉超声筛查是避免 CABG 后并发症的可行且有效的策略。

试验注册

NCT03516929,于 2018 年 4 月 24 日注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe2f/7525944/73a06fe8479a/13019_2020_1340_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe2f/7525944/73a06fe8479a/13019_2020_1340_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe2f/7525944/73a06fe8479a/13019_2020_1340_Fig1_HTML.jpg

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Contemporary incidence and risk factors for carotid artery disease in patients referred for coronary artery bypass surgery.
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ACCF/ACR/AIUM/ASE/ASN/ICAVL/SCAI/SCCT/SIR/SVM/SVS/SVU [corrected] 2012 appropriate use criteria for peripheral vascular ultrasound and physiological testing part I: arterial ultrasound and physiological testing: a report of the American College of Cardiology Foundation appropriate use criteria task force, American College of Radiology, American Institute of Ultrasound in Medicine, American Society of Echocardiography, American Society of Nephrology, Intersocietal Commission for the Accreditation of Vascular Laboratories, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, Society for Interventional Radiology, Society for Vascular Medicine, Society for Vascular Surgery, [corrected] and Society for Vascular Ultrasound. [corrected].ACCF/ACR/AIUM/ASE/ASN/ICAVL/SCAI/SCCT/SIR/SVM/SVS/SVU [更正] 2012 年外周血管超声和生理检查适用标准:动脉超声和生理检查:美国心脏病学会基金会适用标准特别工作组、美国放射学会、美国超声医学学会、美国超声心动图学会、美国肾脏病学会、血管实验室认证协会、心血管血管造影和介入学会、心血管计算机断层成像学会、介入放射学会、血管医学学会、血管外科学会、[更正]和血管超声学会的报告。[更正]。
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