Huckaba C E, Frewin D B, Downey J A, Tam H S, Darling R C, Cheh H Y
Arch Phys Med Rehabil. 1976 Jun;57(6):268-74.
Dynamic sudomotor response to changing ambient temperatures (30 C to 45 C) was measured on eight unacclimatized subjects including five normals, two paraplegics and one anhidrotic patient. Mean sweating rates, computed from five simultaneously observed local rates, were used to compare the overall sudomotor response to heat exposure of the three groups. In the normal subjects, an average rise of 0.34 C in oral temperature and 2.5 C in mean skin temperature was found in a period of 65 minutes. The paraplegics developed a higher rise in both oral and skin temperatures due to a lower sweating rate in the insentinent region. (Insentient describes the sensory state of the skin below the level of the lesion where the subject has no awareness of surface stimulation). A relatively higher sweating rate was observed on the forehead and the cyclic sweating behavior of the insentient skin was not synchronous with that in the sentient. (Sentient describes the state where partial or total awareness is elicited by stimulation). The anhidrotic patient showed a twofold increase of moisture loss from the skin but no cyclic pattern of sweat gland activity on exposure to heat. In this case, hyperthermia developed with a rise in oral temperature of 1.1 C in 52 minutes versus 0.4 C rise in the controls in a period of 63 minutes.
在8名未适应环境的受试者身上测量了对环境温度变化（30摄氏度至45摄氏度）的动态出汗反应，其中包括5名正常人、2名截瘫患者和1名无汗症患者。通过同时观察5个局部出汗率计算出的平均出汗率，用于比较三组受试者对热暴露的整体出汗反应。在正常受试者中，在65分钟内口腔温度平均升高0.34摄氏度，平均皮肤温度升高2.5摄氏度。由于无感觉区域出汗率较低，截瘫患者的口腔和皮肤温度升高幅度更大。（无感觉描述的是病变水平以下皮肤的感觉状态，受试者对该区域的表面刺激没有意识）。在前额观察到相对较高的出汗率，且无感觉皮肤的周期性出汗行为与有感觉皮肤不同步。（有感觉描述的是刺激引发部分或完全意识的状态）。无汗症患者在受热时皮肤水分流失增加了两倍，但汗腺活动没有周期性模式。在这种情况下，体温过高，在52分钟内口腔温度升高1.1摄氏度，而对照组在63分钟内升高0.4摄氏度。
