[Morphological changes in triploidy in human ontogeny].

Cytological and morphological data of 187 spontaneous abortuses, 25 fetuses and infants with triploidy described in literature and 6 proper triploid abortuses were analyzed. It was established that in spite of polymorphism of phenotypical manifestations of triploidy in ontogenesis there are a number of permanent, often combining morphological changes (asymmetry of the body, syndactylism of the III--IV fingers and toes, anomalies in the nervous and genito-urinary system). These features in addition Institute of Medical Genetics, USSR Acad. Med. Sci., and Institute of Obstetrics and Gynecology, Ministry of Health, USSR. To dysplasias present in other chromosomal disorders, allow establishing the syndrom of triploidy in man and to diagnose the disease with great probability. Hydropic and cystose degeneration of the chorion villi met in 85% of cases of triploidy has but external resemblance with true vesicular mole which has normal karyotype. Cytogenetical and morphofunctional differences between them were noted.