Dvorakovskaia I V
Arkh Patol. 1976;38(3):52-7.
A total of 14 observations on mucoepidermoid tumours of the bronchi were studied. Patients were of the age of 29-75 years. Nine tumours were exophytic, 3-- endobronchial, 2--of the type "Iceberg". A definite interdependence was observed between the anatomic form of the tumours and histological structure thereof. All the variants of the multi-stratified structures (pseudoepidermoid, spindle-cellular, clear-cellular, and others) were characterized by the absence of cornification, and they fully comply with the notion of ateleplasia suggested by V.G. Garshin. Similarly, in mucigenesis there was not observed metaplasia, but maturation of cells in the direction natural for the respiratory epithelium. Mucigenesis could be realized in two ways: in glandular tubes or by mucification of individual cells of the pseudoepidermoid layers. In the latter case the polar differentiation of cells was absent. Mucoepidermoid tumours may develop both from mucous glands and from tegmental epithelium of the bronchi.
共研究了14例支气管黏液表皮样肿瘤的观察病例。患者年龄在29至75岁之间。9例肿瘤为外生性，3例为支气管内型，2例为“冰山”型。观察到肿瘤的解剖形态与其组织结构之间存在明确的相互依存关系。所有多层结构变体（假表皮样、梭形细胞、透明细胞等）的特征均为无角化，且完全符合V.G.加尔申提出的发育不全概念。同样，在黏液生成过程中未观察到化生，而是细胞朝着呼吸道上皮自然的方向成熟。黏液生成可通过两种方式实现：在腺管中或通过假表皮样层单个细胞的黏液化。在后一种情况下，细胞不存在极性分化。黏液表皮样肿瘤可起源于黏液腺和支气管的被覆上皮。
