范科尼贫血患者紫外线照射后DNA修复缺陷。
Faulty DNA repair following ultraviolet irradiation in Fanconi's anemia.
作者信息
Poon P K, Parker J W, O'Brien R L
出版信息
Basic Life Sci. 1975;5B:821-4. doi: 10.1007/978-1-4684-2898-8_64.
PMID:127579
Abstract
Fibroblasts from a patient with Fanconi's anemia were deficient in their ability to excise UV-induced pyrimidine dimers from their DNA but were capable of single-strand break production and unscheduled DNA synthesis.
摘要
范科尼贫血患者的成纤维细胞切除DNA中紫外线诱导的嘧啶二聚体的能力存在缺陷，但能够产生单链断裂并进行DNA的非常规合成。
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