短杆菌肽A的化学性质与序列
Chemical nature and sequence of alamethicin.
作者信息
Martin D R, Williams R J
出版信息
Biochem J. 1976 Feb 1;153(2):181-90. doi: 10.1042/bj1530181.
Abstract
An n.m.r. spectroscopy study of pure alamethicin shows it to be a linear polypeptide of 19 residues. The N-terminus is blocked by an acetyl group, and the eighteenth residue, glutamic acid, is linked by an amide bond on its side chain to phenylalaninol (Fig. 6). The new formula is confirmed by a comparison between pure chemical compounds and the products of partial hydrolysis.
摘要
对纯短杆菌肽进行的核磁共振光谱研究表明，它是一种由19个残基组成的线性多肽。N端被乙酰基封闭，第18个残基谷氨酸通过其侧链上的酰胺键与苯丙氨醇相连（图6）。通过纯化学化合物与部分水解产物之间的比较，证实了新的分子式。
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