家兔体内N-甲基精氨酸、N,N-二甲基精氨酸和N,N'-二甲基精氨酸的分解代谢研究。
Studies on the catabolism of Ng-methylarginine, Ng, Ng-dimethylarginine and Ng, Ng-dimethylarginine in the rabbit.
作者信息
McDermott J R
出版信息
Biochem J. 1976 Jan 15;154(1):179-84. doi: 10.1042/bj1540179.
Abstract
- The routes of elimination of Ng-methylarginine, Ng, Ng-dimethylarginine and Ng, Ng-dimethylarginine were investigated in the rabbit. 2. Analyses showed low plasma concentrations of these amino acids (around 1 nmol/ml) and ratios similar to those found in tissue proteins. The concentrations of these amino acids in extracts of brain, kidney, liver and spleen were similar except that liver had a lower concentration of Ng-methylarginine and Ng, Ng-dimethylarginine. Cerebrospinal fluid contained traces of each amino acid.
摘要
- 在兔子身上研究了N-甲基精氨酸、N,N-二甲基精氨酸和N,N'-二甲基精氨酸的消除途径。2. 分析表明，这些氨基酸的血浆浓度较低（约1纳摩尔/毫升），其比例与组织蛋白中的比例相似。脑、肾、肝和脾提取物中这些氨基酸的浓度相似，只是肝脏中N-甲基精氨酸和N,N-二甲基精氨酸的浓度较低。脑脊液中含有微量的每种氨基酸。
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