Rous-Whipple Award Lecture. How tumors make bad blood vessels and stroma.
作者信息
Dvorak Harold F
机构信息
Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA.
出版信息
Am J Pathol. 2003 Jun;162(6):1747-57. doi: 10.1016/s0002-9440(10)64309-x.
Abstract
摘要
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Vascular permeability factor/vascular endothelial growth factor induces lymphangiogenesis as well as angiogenesis.血管通透性因子/血管内皮生长因子可诱导淋巴管生成以及血管生成。
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Ultrastructural studies define soluble macromolecular, particulate, and cellular transendothelial cell pathways in venules, lymphatic vessels, and tumor-associated microvessels in man and animals.超微结构研究确定了人和动物的小静脉、淋巴管及肿瘤相关微血管中可溶性大分子、颗粒及细胞的跨内皮细胞途径。
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