Le Lan Caroline, Dinasquet Michel, Salim Bassam, Pagenault Maël, Audouin Anne-Françoise, Turlin Bruno, Donnio Pierre-Yves, Bretagne Jean-François, Gosselin Michel, Heresbach Denis
Service des Maladies de l'Appareil Digestif, CHU Rennes.
Gastroenterol Clin Biol. 2003 Apr;27(4):416-9.
We describe a case of Whipple's disease confirmed by clinical, histological, bacteriological and molecular criteria. The duodenal involvement was associated with the presence of an endoscopic and histological enterocolitis. Final diagnosis of small bowel and colonic involvement by Whipple's disease was confirmed by histology and molecular biology. We review the literature on extra duodenal involvement. We underline the fact that enterocolitis in Whipple's disease is non-specific. We also discuss the other causes of intestinal mucosal infiltration by macrophages.