静脉麻醉药超敏反应的识别与定量分析。

Identification and quantitation of hypersensitivity reactions to intravenous anaesthetic agents.

作者信息

Watkins J, Udnoon S, Appleyard T N, Thornton J A

出版信息

Br J Anaesth. 1976 May;48(5):457-61. doi: 10.1093/bja/48.5.457.

DOI:10.1093/bja/48.5.457

Abstract

It is not possible to distinguish between direct pharmacological effects and immune-mediated hypersensitivity reactions by clinical observation alone and errors may occur in the absence of laboratory tests. A convenient and simple test is the measurement of plasma complement C3 consumption and conversion in sequential blood samples taken at intervals over the 24 h following an adverse response.

摘要

仅通过临床观察无法区分直接药理作用和免疫介导的超敏反应，在没有实验室检测的情况下可能会出现错误。一个方便简单的检测方法是在不良反应发生后的24小时内，间隔采集系列血样，检测血浆补体C3的消耗和转化情况。