Selimoğlu E, Selimoğlu M A, Orbak Z
Department of Otolaryngology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.
J Int Med Res. 2003 Mar-Apr;31(2):84-7. doi: 10.1177/147323000303100204.
Faltering growth may be associated with adenotonsillar hypertrophy, but its pathophysiological mechanism is unclear. This study included 29 pre-pubertal children with obstructive adenotonsillar hypertrophy, and aimed to investigate the probable difference in energy intake and serum insulin-like growth factor 1 (IGF-1) and insulin-like growth factor binding protein 3 (IGFBP-3) levels before and 6 months after adenotonsillectomy. Weight and height standard deviation scores, energy intake per kilogram and serum IGF-1 levels were found to be significantly higher 6 months after adenotonsillectomy, indicating that adenotonsillar hypertrophy is associated with poor growth.
生长发育迟缓可能与腺样体扁桃体肥大有关，但其病理生理机制尚不清楚。本研究纳入了29例青春期前患有阻塞性腺样体扁桃体肥大的儿童，旨在调查腺样体扁桃体切除术前及术后6个月能量摄入、血清胰岛素样生长因子1（IGF-1）和胰岛素样生长因子结合蛋白3（IGFBP-3）水平的可能差异。结果发现，腺样体扁桃体切除术后6个月，体重和身高标准差评分、每千克能量摄入量和血清IGF-1水平均显著升高，表明腺样体扁桃体肥大与生长发育不良有关。
Zotero 插件