Hoban Timothy F
Department of Pediatrics, L3227, Women's Hospital, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.
Curr Treat Options Neurol. 2005 Sep;7(5):353-61. doi: 10.1007/s11940-005-0028-9.
Despite increasing recognition of childhood obstructive sleep apnea syndrome (OSAS) as a significant public health problem, treatment of the condition remains inconsistent. Some children are screened using polysomnography and treated only when objective respiratory disturbances are identified. Many others receive adenotonsillectomy based only on signs and symptoms of upper airway obstruction without ever having a formal sleep study. Outcome-based data regarding the effectiveness of adenotonsillectomy, continuous positive airway pressure, and other treatments for childhood OSAS remain extremely limited. In this article, the major therapeutic options for treatment of childhood OSAS are reviewed. Adenotonsillectomy remains the most frequently used treatment for uncomplicated OSAS in children, but residual airway obstruction persists in a notable minority of patients. Nasal continuous positive airway pressure is used for children who are not good surgical candidates or who have failed previous surgical treatment, but is sometimes not tolerated by young children or their parents. Various alternative treatments are used on an individualized basis for children who cannot use the two first-line therapies for sleep apnea.
尽管儿童阻塞性睡眠呼吸暂停综合征(OSAS)作为一个重大的公共卫生问题越来越受到重视,但该病症的治疗仍不一致。一些儿童通过多导睡眠图进行筛查,仅在发现客观呼吸紊乱时才进行治疗。许多其他儿童仅根据上呼吸道阻塞的体征和症状接受腺样体扁桃体切除术,从未进行过正式的睡眠研究。关于腺样体扁桃体切除术、持续气道正压通气及其他治疗儿童OSAS有效性的基于结果的数据仍然极为有限。在本文中,对儿童OSAS的主要治疗选择进行了综述。腺样体扁桃体切除术仍然是治疗儿童单纯性OSAS最常用的方法,但仍有相当一部分患者存在残余气道阻塞。鼻持续气道正压通气用于不适合手术或先前手术治疗失败的儿童,但幼儿或其父母有时无法耐受。对于不能使用前两种睡眠呼吸暂停一线治疗方法的儿童,会根据个体情况采用各种替代治疗方法。