Jost Wolfgang H
Fachbereich Neurologie und Klin. Neurophysiologie, Deutsche Klinik für Diagnostik, Aukammallee 33, 65191 Wiesbaden, Germany.
J Neurol. 2003 Feb;250 Suppl 1:I28-30. doi: 10.1007/s00415-003-1105-z.
Most patients with Parkinson's disease experience autonomic dysfunction at some point in the course of their disease. In contrast to autonomic dysregulation in multisystem atrophy, they are less severe, and they frequently cause troublesome symptoms only in advanced stages of the disease. The quality of life is nevertheless substantially restricted. Cardiovascular, gastrointestinal and urogenital autonomic dysfunction is predominant. Appropriate diagnosis and treatment can greatly benefit the patient. An interdisciplinary approach is desirable in most cases.
大多数帕金森病患者在其病程中的某个阶段会出现自主神经功能障碍。与多系统萎缩中的自主神经调节异常不同,帕金森病患者的自主神经功能障碍症状较轻,且通常仅在疾病晚期才会引起令人困扰的症状。然而,患者的生活质量仍会受到很大限制。心血管、胃肠道和泌尿生殖系统的自主神经功能障碍较为常见。恰当的诊断和治疗能使患者受益匪浅。在大多数情况下,采用多学科方法是可取的。