喜马拉丁A，一种来自中华石松的新型C27N3型生物碱。

Himeradine A, a novel C27N3-type alkaloid from Lycopodium chinense.

作者信息

Morita Hiroshi, Hirasawa Yusuke, Kobayashi Jun'ichi

机构信息

Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.

出版信息

J Org Chem. 2003 May 30;68(11):4563-6. doi: 10.1021/jo034294t.

DOI:10.1021/jo034294t

PMID:12762772

Abstract

A novel C(27)N(3)-type Lycopodium alkaloid consisting of a fastigiatine-type skeleton (C(16)N(2)) and a quinolizidine moiety (C(11)N), himeradine A (1), has been isolated from the club moss Lycopodium chinense, and the structure and relative stereochemistry were elucidated on the basis of spectroscopic data.

摘要

从中国石松中分离出一种新型的C(27)N(3)型石松生物碱——喜美拉丁A（1），它由一个扁枝石松碱型骨架（C(16)N(2)）和一个喹诺里西啶部分（C(11)N）组成，并根据光谱数据阐明了其结构和相对立体化学。