Apotirucallane and Tirucallane triterpenoids from Luvunga sarmentosa.

作者信息

Kamperdick Christine, Lien Trinh Phuong, Adam Guenter, Sung Tran Van

机构信息

Institute of Chemistry, National Center for Natural Science and Technology of Vietnam, Hoang Quoc Viet Road, Cau Giay, Hanoi, Vietnam.

出版信息

J Nat Prod. 2003 May;66(5):675-8. doi: 10.1021/np020458+.

DOI:10.1021/np020458+

PMID:12762805

Abstract

The leaves of Luvunga sarmentosa yielded two new apotirucallane triterpenoids, 3-epi-skimmiarepin A (1) and 21,23-epoxy-7alpha,21-dihydroxyapotirucalla-14,24-dien-3-one (2), and a new tirucallane triterpene, 3-epi-flindissol (3). Because of a hemiacetal functionality at C-21, all compounds occurred as mixtures of 21-epimers. 3-epi-Skimmiarepin A (1) and 3-epi-flindissol (3) were oxidized to the corresponding gamma-lactones. The structures have been elucidated on the basis of mass and NMR spectroscopic methods.

摘要