来自苦瓜的葫芦烷型三萜类化合物。
Cucurbitane-type triterpenoids from Momordica charantia.
作者信息
Chang Chi-I, Chen Chiy-Rong, Liao Yun-Wen, Cheng Hsueh-Ling, Chen Yo-Chia, Chou Chang-Hung
机构信息
Graduate Institute of Biotechnology, National Pingtung University of Science and Technology, Pingtung 912, Taiwan, Republic of China.
出版信息
J Nat Prod. 2006 Aug;69(8):1168-71. doi: 10.1021/np068008v.
Five new cucurbitane-type triterpenes, (23E)-25-methoxycucurbit-23-ene-3beta,7beta-diol (1), (23E)-cucurbita-5,23,25-triene-3beta,7beta-diol (2), (23E)-25-hydroxycucurbita-5,23-diene-3,7-dione (3), (23E)-cucurbita-5,23,25-triene-3,7-dione (4), and (23E)-5beta,19-epoxycucurbita-6,23-diene-3beta,25-diol (5), together with one known triterpene, (23E)-5beta,19-epoxy-25-methoxycucurbita-6,23-dien-3beta-ol (6), have been isolated from the methanol extract of the stems of Momordica charantia. The structures of the new compounds were elucidated by spectroscopic methods.
从苦瓜茎的甲醇提取物中分离出了五种新的葫芦烷型三萜，即(23E)-25-甲氧基葫芦-23-烯-3β,7β-二醇（1）、(23E)-葫芦-5,23,25-三烯-3β,7β-二醇（2）、(23E)-25-羟基葫芦-5,23-二烯-3,7-二酮（3）、(23E)-葫芦-5,23,25-三烯-3,7-二酮（4）和(23E)-5β,19-环氧葫芦-6,23-二烯-3β,25-二醇（5），以及一种已知的三萜(23E)-5β,19-环氧-25-甲氧基葫芦-6,23-二烯-3β-醇（(6)）。通过光谱方法阐明了新化合物的结构。
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