[类固醇激素与谷氨酸脱氢酶的相互作用]
[Interaction of steroid hormones with glutamate dehydrogenase].
作者信息
Titova G V, Kliueva N N
出版信息
Biokhimiia. 1976 Mar;41(3):487-90.
PMID:1276282
Abstract
The inhibitory action of sex hormones on the glutamate dehydrogenase activity is due to their binding to the enzyme protein. No binding of sex hormones to glutamate dehydrogenase is observed in the presence of L-amino acids, preventing the enzyme dissociation. Under those conditions the enzyme sensitivity to the inhibitory action of the hormones sharply decreases.
摘要
性激素对谷氨酸脱氢酶活性的抑制作用是由于它们与酶蛋白结合。在L-氨基酸存在的情况下，未观察到性激素与谷氨酸脱氢酶结合，从而防止了酶的解离。在这些条件下，酶对激素抑制作用的敏感性急剧下降。
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