Titova G V, Kliueva N N
Biokhimiia. 1977 Apr;42(4):635-8.
The effect of sex hormones on the activity of glutamate dehydrogenase from beef liver was studied in vitro. The inhibitory effect of the hormones was relieved both when the guanidine groups of the enzyme were blocked and when L-arginine was added to the reaction mixture. The data obtained suggest that the guanidine groups of the arginine residues of the enzyme are involved in the realization of the inhibitory effect of the hormones.
在体外研究了性激素对牛肝谷氨酸脱氢酶活性的影响。当酶的胍基被封闭以及向反应混合物中添加L-精氨酸时,激素的抑制作用均得到缓解。所获得的数据表明,该酶精氨酸残基的胍基参与了激素抑制作用的实现。