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[关于谷氨酸脱氢酶与性激素的相互作用]

[On glutamate dehydrogenase interaction with sex hormones].

作者信息

Titova G V, Kliueva N N

出版信息

Biokhimiia. 1977 Apr;42(4):635-8.

PMID:558001
Abstract

The effect of sex hormones on the activity of glutamate dehydrogenase from beef liver was studied in vitro. The inhibitory effect of the hormones was relieved both when the guanidine groups of the enzyme were blocked and when L-arginine was added to the reaction mixture. The data obtained suggest that the guanidine groups of the arginine residues of the enzyme are involved in the realization of the inhibitory effect of the hormones.

摘要

在体外研究了性激素对牛肝谷氨酸脱氢酶活性的影响。当酶的胍基被封闭以及向反应混合物中添加L-精氨酸时,激素的抑制作用均得到缓解。所获得的数据表明,该酶精氨酸残基的胍基参与了激素抑制作用的实现。

相似文献

1
[On glutamate dehydrogenase interaction with sex hormones].[关于谷氨酸脱氢酶与性激素的相互作用]
Biokhimiia. 1977 Apr;42(4):635-8.
2
[Effect of steroid hormones on glutamate dehydrogenase activity in rat liver mitochondria].[类固醇激素对大鼠肝线粒体中谷氨酸脱氢酶活性的影响]
Vopr Med Khim. 1978 Jan-Feb;24(1):49-51.
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[Role of guanidine groups of glutamate dehydrogenase arginine residues in the binding of sex hormones].[谷氨酸脱氢酶精氨酸残基的胍基在性激素结合中的作用]
Biokhimiia. 1978 Sep;43(9):1670-3.
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[Effect of thiol reagents on the interaction of glutamate dehydrogenase with sex hormones].[硫醇试剂对谷氨酸脱氢酶与性激素相互作用的影响]
Biokhimiia. 1976 May;41(5):903-5.
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[Influence of effectors on molecular weight and activity of glutamate dehydrogenase (GluDH) from bovine liver in vitro. II. Activity of GluDH and its subunits].[效应物对牛肝谷氨酸脱氢酶(GluDH)体外分子量及活性的影响。II. GluDH及其亚基的活性]
Z Naturforsch B. 1970 Mar;25(3):273-6.
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[Effect of insulin and steroid hormones on the conformation and activity of enzyme proteins].[胰岛素和类固醇激素对酶蛋白构象及活性的影响]
Vopr Med Khim. 1977 Jan-Feb(1):59-65.
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[The role of the chemical structure of steroid hormones in inhibiting peroxidative lipid oxidation in mitochondrial membranes].[甾体激素化学结构在抑制线粒体膜脂质过氧化中的作用]
Vopr Med Khim. 1974 Jul-Aug;20(4):359-62.
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Effect of sex hormones on the concentrations of plasma kininogen in the female rat.性激素对雌性大鼠血浆激肽原浓度的影响。
Br J Pharmacol. 1971 Oct;43(2):421P-422P.
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[Interaction of steroid hormones with glutamate dehydrogenase].[类固醇激素与谷氨酸脱氢酶的相互作用]
Biokhimiia. 1976 Mar;41(3):487-90.
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[The role of guanidine groups of arginine residues of Na, K-ATPase and glutamate dehydrogenase in an interaction with cholesterol].[钠钾-ATP酶和谷氨酸脱氢酶精氨酸残基的胍基在与胆固醇相互作用中的作用]
Ukr Biokhim Zh (1978). 1989 Sep-Oct;61(5):29-34.