Broadley S, Croser D, Cottrell J, Creevy M, Teo E, Yiu D, Pathi R, Taylor J, Thompson P D
Department of Neurology, Royal Adelaide Hospital, North Terrace, SA 5000, Australia.
J Clin Neurosci. 2003 May;10(3):300-5. doi: 10.1016/s0967-5868(03)00022-5.
Dysphagia following acute stroke frequently necessitates prolonged enteral feeding. There is evidence that early enteral feeding via percutaneous endoscopic gastrostomy (PEG) is both beneficial and safe. The aim of this study was to identify predictors of prolonged dysphagia. The subjects were 149 consecutive patients admitted with acute stroke. Clinical findings and imaging results were prospectively collected, and subsequent progress recorded. Subjects were divided into 3 groups for analysis: no dysphagia; transient dysphagia (< or =14 days); or prolonged dysphagia (>14 days). Validity of the water swallow test as a predictor of aspiration pneumonia was confirmed. Significant associations for prolonged dysphagia were seen with stroke severity, dysphasia and lesions of the frontal and insular cortex on brain imaging. These results indicate that it may be possible to predict patients who will develop prolonged significant dysphagia following acute stroke thereby facilitating referral for insertion of PEG at an earlier time point.
急性中风后吞咽困难常常需要长期肠内喂养。有证据表明,通过经皮内镜下胃造口术(PEG)进行早期肠内喂养既有益又安全。本研究的目的是确定长期吞咽困难的预测因素。研究对象为149例连续收治的急性中风患者。前瞻性收集临床发现和影像学结果,并记录后续进展。将研究对象分为3组进行分析:无吞咽困难;短暂吞咽困难(≤14天);或长期吞咽困难(>14天)。证实了饮水试验作为吸入性肺炎预测指标的有效性。脑成像显示,长期吞咽困难与中风严重程度、言语困难以及额叶和岛叶皮质病变存在显著关联。这些结果表明,有可能预测急性中风后会出现长期严重吞咽困难的患者,从而便于在更早的时间点转介进行PEG置入。