Senagore Anthony J, Delaney Conor P, Madboulay Khaled, Brady Karen M, Fazio Victor W
Department of Colorectal Surgery, Cleveland Clinic Foundation, OH 44195, USA.
J Gastrointest Surg. 2003 May-Jun;7(4):558-61. doi: 10.1016/s1091-255x(02)00124-5.
Obese patients carry a higher risk of wound complications and cardiopulmonary complications along with a higher incidence of comorbidity, all of which have the potential to affect outcome after a variety of surgical procedures. The data regarding outcomes after laparoscopic colectomy in obese and nonobese patients are limited. The purpose of this report was to compare the outcome of laparoscopic bowel resection in obese and nonobese patients. All patients prospectively entered into a laparoscopic bowel resection database from March 1999 to December 2001, who underwent a segmental colectomy for any pathologic condition, were analyzed. Patients with a body mass index above 30 were defined as obese, and patients with a body mass index below 30 were defined as nonobese. Data collected included age, sex, duration of operation, body mass index, American Society of Anesthesiologists score, operative procedure, diagnosis, complications relating to length of hospital stay, mortality, and readmission within 30 days of discharge. Statistical analysis consisted of Student's t test and chi-square analysis where appropriate, with significance set at P < 0.05. A total of 260 patients were evaluated (201 [77.3%] in the nonobese group and 59 [22.7%] in the obese group). There were no significant differences between the two groups with respect to age, sex, operative procedure, length of hospital stay, or readmission rates. The obese group had significantly more conversions to an open procedure (23.7% vs. 10.9%), a longer operative duration (109 minutes vs. 94 minutes), a higher morbidity rate (22% vs. 13%) and a higher anastomotic leakage rate (5.1% vs. 1.2%). This large experience with laparoscopic colectomy for a variety of conditions demonstrates that despite higher conversion rates, an increased risk of pulmonary complications, and anastomotic leakage rates in obese laparoscopic patients that parallel those of open surgery, laparoscopic colectomy can be performed safely in both obese and nonobese patients with the similar benefit of a shorter hospital stay in both groups.
肥胖患者伤口并发症和心肺并发症的风险更高,合并症发生率也更高,所有这些都有可能影响各种外科手术后的结果。关于肥胖和非肥胖患者腹腔镜结肠切除术后结果的数据有限。本报告的目的是比较肥胖和非肥胖患者腹腔镜肠切除的结果。对1999年3月至2001年12月前瞻性纳入腹腔镜肠切除数据库、因任何病理状况接受节段性结肠切除术的所有患者进行了分析。体重指数高于30的患者被定义为肥胖患者,体重指数低于30的患者被定义为非肥胖患者。收集的数据包括年龄、性别、手术时间、体重指数、美国麻醉医师协会评分、手术方式、诊断、与住院时间相关的并发症、死亡率以及出院后30天内的再入院情况。统计分析在适当情况下采用学生t检验和卡方分析,显著性设定为P<0.05。共评估了260例患者(非肥胖组201例[77.3%]和肥胖组59例[22.7%])。两组在年龄、性别、手术方式、住院时间或再入院率方面无显著差异。肥胖组转为开放手术的比例显著更高(23.7%对10.9%),手术时间更长(109分钟对94分钟),发病率更高(22%对13%),吻合口漏率更高(5.1%对1.2%)。这项针对各种情况的腹腔镜结肠切除术的大量经验表明,尽管肥胖腹腔镜患者的中转率更高、肺部并发症风险增加以及吻合口漏率与开放手术相当,但肥胖和非肥胖患者均可安全地进行腹腔镜结肠切除术,两组患者住院时间均较短,获益相似。