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腹腔镜结肠切除术对病态肥胖患者安全吗?

Is the laparoscopic approach to colectomy safe for the morbidly obese?

机构信息

Department of Colorectal Surgery, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

出版信息

Surg Endosc. 2010 Jun;24(6):1336-40. doi: 10.1007/s00464-009-0770-2. Epub 2009 Dec 24.

Abstract

BACKGROUND

The feasibility and safety of laparoscopic colectomy (LC) for morbidly obese patients has not been reported previously. This study aimed to assess the clinical outcomes of patients with a body mass index (BMI) of 40 kg/m(3) or more who undergo laparoscopic colorectal surgery.

METHODS

Prospectively accrued data for patients with a BMI of 40 kg/m(3) or more (group A) who undergo LC were compared with those for patients with BMI lower than 30 kg/m(3) (group B) matched for year of surgery, indication, operating surgeon, and type of procedure.

RESULTS

Each group had 36 patients. The group A patients were significantly younger (54 vs. 61 years; P = 0.04), had higher American Society of Anesthesiology (ASA) scores (P = 0.001), and had diabetes mellitus (P = 0.04). The indications for surgery and the operations performed were similar. The two groups had similar operating times (177.9 vs. 136.4 min; P = 0.12), estimated blood losses (222.3 vs. 157 ml; P = 0.1), median lengths of hospital stay (LOS) (4.5 vs. 4 days; P = 0.2), and returns of bowel function (4.2 vs. 3.9 days; P = 0.45). Group A had significantly longer incisions (6.9 vs. 5 cm; P = 0.02). Conversions (5 vs. 3 patients; P = 0.7), readmissions (12 vs. 6 patients; P = 0.46), reoperations (5 vs. 3 patients; P = 0.17), wound infections (7 vs. 2 patients; P = 0.14), anastomotic leaks (3 vs. 2 patients; P = 0.7), and abdominal abscesses (3 vs. 2 patients; P = 0.7) were more predominant in group A, although the differences did not reach statistical significance.

CONCLUSIONS

Laparoscopic colectomy is feasible for morbidly obese patients and results in recovery of intestinal function and LOS equivalent to that for nonobese patients. As expected, morbidity and conversion rates are higher for morbidly obese patients undergoing LC than for nonobese patients.

摘要

背景

腹腔镜结肠切除术(LC)治疗病态肥胖患者的可行性和安全性此前尚未报道。本研究旨在评估 BMI 为 40kg/m(3)或更高的患者接受腹腔镜结直肠手术的临床结果。

方法

前瞻性收集 BMI 为 40kg/m(3)或更高(A 组)的患者接受 LC 的数据,并与 BMI 低于 30kg/m(3)(B 组)的患者进行比较,两组患者在手术年份、手术指征、手术医生和手术类型方面相匹配。

结果

每组各有 36 例患者。A 组患者明显更年轻(54 岁比 61 岁;P = 0.04),ASA 评分更高(P = 0.001),且患有糖尿病(P = 0.04)。手术指征和手术方式相似。两组的手术时间(177.9 分钟比 136.4 分钟;P = 0.12)、估计失血量(222.3 毫升比 157 毫升;P = 0.1)、中位住院时间(4.5 天比 4 天;P = 0.2)和肠功能恢复时间(4.2 天比 3.9 天;P = 0.45)相似。A 组切口明显更长(6.9 厘米比 5 厘米;P = 0.02)。中转开腹(5 例比 3 例;P = 0.7)、再次入院(12 例比 6 例;P = 0.46)、再次手术(5 例比 3 例;P = 0.17)、切口感染(7 例比 2 例;P = 0.14)、吻合口漏(3 例比 2 例;P = 0.7)和腹部脓肿(3 例比 2 例;P = 0.7)更常见,但差异无统计学意义。

结论

腹腔镜结肠切除术对病态肥胖患者是可行的,并且其肠功能恢复和住院时间与非肥胖患者相当。正如预期的那样,病态肥胖患者接受 LC 的发病率和转化率高于非肥胖患者。

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