Govorova L V, Teplov S I
Biull Eksp Biol Med. 1976 Feb;81(2):177-9.
The action of hypoxic and cytotoxic hypoxia on the creatine phosphokinase activity in the blood plasma, cardiac and hepatic tissue, cerebral tissue, as well as on the nuclear and mitochondrial cerebral fractions was investigated. Oxygen deficiency was followed by significant changes of the creatine kinase activity in all the tissues and cell fractions under investigation. The type of changes depended on the isoenzyme tissue perculiarities, as well as on the state of the enzyme oxidative phosphorylation systems and membrane permeability.
研究了低氧和细胞毒性低氧对血浆、心脏和肝脏组织、脑组织中的肌酸磷酸激酶活性以及对脑细胞核和线粒体组分的作用。缺氧后，所有被研究的组织和细胞组分中的肌酸激酶活性都发生了显著变化。变化的类型取决于同工酶的组织特性，以及酶氧化磷酸化系统和膜通透性的状态。
