[间质细胞在肾髓质前列腺素合成中的作用]
[Role of interstitial cells in prostaglandin synthesis in the kidney medulla].
作者信息
Sokolova R I, Vikhert A M
出版信息
Biull Eksp Biol Med. 1976;81(4):503-5.
PMID:1276464
Abstract
An electron-microscopic study of the interstitial cells of the medulla of the kidneys was carried out after the administration of the inhibitor of prostaglandine synthesis -- indometacine. Under these conditions the amount of lipid granules in the interstitial cells increased significantly. The authors consider the results of study to be an evident proof of participation of lipid granules in the synthetic function of the interstitial cells as a "depôt" of a chemical precursor of prostaglandines synthesized by the interstitial cells.
摘要
在给予前列腺素合成抑制剂——消炎痛后，对肾髓质间质细胞进行了电子显微镜研究。在这些条件下，间质细胞中脂质颗粒的数量显著增加。作者认为该研究结果明显证明脂质颗粒作为间质细胞合成的前列腺素化学前体的“储存库”参与了间质细胞的合成功能。
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