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Studies on plasma membranes. XXIII. Hormone-like action of concanavalin A on liver plasma membranes: inhibition of (Na+-K+)ATPase.

作者信息

Luly P, Emmelot P

出版信息

Chem Biol Interact. 1975 Nov;11(5):377-85. doi: 10.1016/0009-2797(75)90006-x.

DOI:10.1016/0009-2797(75)90006-x
PMID:127672
Abstract

Concanavalin A inhibits the (Na+-K+)-ATPase activity of isolated rat-liver plasma membranes, while leaving the Mg2+-ATPase unaffected. Glucagon and cyclic AMP act supplementary to the lectin in the inhibition. The lectin effect is counteracted by insulin and L-epinephrine, and is completely abolished by the beta-adrenergic blocking agent propranolol. Results are discussed on the basis of the known interactions of concanavalin A with plasma membrane components, including its hormone-like action.

摘要

相似文献

1
Studies on plasma membranes. XXIII. Hormone-like action of concanavalin A on liver plasma membranes: inhibition of (Na+-K+)ATPase.
Chem Biol Interact. 1975 Nov;11(5):377-85. doi: 10.1016/0009-2797(75)90006-x.
2
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[Effect of adrenaline on the ATPase activity of rat liver plasma membranes].[肾上腺素对大鼠肝细胞膜ATP酶活性的影响]
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Nature of the lectin-induced activation of plasma membrane Mg2+ATPase.
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引用本文的文献

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Ecto-enzymes of mammary gland and its tumours. Ca2+- or Mg2+-stimulated adenosine triphosphatase and its perturbation by concanavalin A.乳腺及其肿瘤的外切酶。钙或镁刺激的三磷酸腺苷酶及其受伴刀豆球蛋白A的干扰
Biochem J. 1980 Oct 1;191(1):45-51. doi: 10.1042/bj1910045.
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[Biology of lectins and their application in clinical biochemistry (author's transl)].[凝集素的生物学及其在临床生物化学中的应用(作者译)]
Klin Wochenschr. 1977 Apr 15;55(8):359-73. doi: 10.1007/BF01488621.