Reid H A
Br Med J. 1976 Jul 17;2(6028):153-6. doi: 10.1136/bmj.2.6028.153.
Ninety-five cases of adder bite that have occurred in Britain over the past 100 years are reviewed. Most bites occurred in men who foolishly picked up the adder. Three-quarters of the victims reached hospital within two hours of the bite. When venom is injected the early symptoms include local swelling and discoloration, vomiting, diarrhoea, and early collapse, which often resolves spontaneously. In severe poisoning persistent or recurrent shock is the main feature. Children recover quickly but adults may take weeks or months to recover, during which there may be considerable disability in the bitten limb. Deaths are rare: only 14 deaths from poisoning were recorded in the past 100 years. In England and Wales only one death from adder bite was recorded in 1950-72, but there were 61 deaths from bee or wasp stings. In most cases simple symptomatic treatment is enough, but all patients should be carefully monitored. With persistent or recurrent shock Zagreb antivenom is indicated; and it should also be considered in adults seen within two hours of the bite to minimise morbidity from local effects.
对过去100年里在英国发生的95例蝰蛇咬伤病例进行了回顾。大多数咬伤发生在那些愚蠢地捡起蝰蛇的男性身上。四分之三的受害者在被咬后两小时内到达医院。注入毒液后,早期症状包括局部肿胀、变色、呕吐、腹泻以及早期虚脱,这些症状通常会自行缓解。在严重中毒时,持续或反复休克是主要特征。儿童恢复迅速,但成年人可能需要数周或数月才能恢复,在此期间被咬肢体可能会有相当程度的功能障碍。死亡情况罕见:在过去100年里仅记录到14例中毒死亡。在英格兰和威尔士,1950年至1972年间仅记录到1例蝰蛇咬伤致死病例,但有61例因蜜蜂或黄蜂蜇伤致死。在大多数情况下,简单的对症治疗就足够了,但所有患者都应仔细监测。对于持续或反复休克,应使用萨格勒布抗蛇毒血清;对于在被咬后两小时内就诊的成年人,也应考虑使用,以将局部影响导致的发病率降至最低。