Urek Roman, Rudan Diana, Frank Branimir, Tomicić Dragutin, Komadina Mladen
Kardiovaskularni odjel Klinika za unutarnje bolesti Medicinskog fakulteta Sveucilista u Zagrebu Opća bolnica Sveti Duh Sveti Duh 64 10000 Zagreb, Hrvatska.
Acta Med Croatica. 2002;56(4-5):181-3.
Primary pulmonary hypertension (PPH) is a rare, progressive and currently incurable disease characterised by an increase in pulmonary artery pressure without a demonstrable cause. When associated with pregnancy, the maternal mortality ranges from 30 to 50%. In this report we present a 26-year old patient diagnosed with primary pulmonary hypertension during her twenty-first week of gestation. She was treated with a low-molecular-weight heparin and sedatives and underwent pregnancy termination without complications. Although cases have been reported with positive maternal and fetal outcome, the available evidence suggests that pregnancy with primary pulmonary hypertension should be avoided. Thus, in cases of pregnancy occurring, a therapeutic abortion is indicated.
原发性肺动脉高压（PPH）是一种罕见的、进行性且目前无法治愈的疾病，其特征是肺动脉压力升高但无明显病因。与妊娠相关时，孕产妇死亡率为30%至50%。在本报告中，我们介绍了一名26岁的患者，她在妊娠21周时被诊断为原发性肺动脉高压。她接受了低分子量肝素和镇静剂治疗，并进行了妊娠终止，无并发症发生。尽管有母婴结局良好的病例报道，但现有证据表明，应避免患有原发性肺动脉高压的患者怀孕。因此，在发生妊娠的情况下，建议进行治疗性流产。
