Kaluzny Jakub J, Orzalkiewicz Alicja, Czajkowski Grzegorz
Department of Ophthalmology, The Ludwik Rydygier's University School of Medical Science, Bydgoszcz, Poland.
Eye Contact Lens. 2003 Jan;29(1):23-6. doi: 10.1097/00140068-200301000-00007.
To evaluate changes in corneal thickness after 2, 4, and 6 weeks of frequent-replacement contact lens wearing.
Twenty-eight patients were fitted with ACUVUE (Johnson & Johnson) contact lenses. Central and peripheral corneal thickness was measured before contact lens fitting and after 2, 4, and 6 weeks of wearing.
Analysis of variance shows that the period of contact lens wearing has no influence on central corneal thickness. After a small increase in the second week, central corneal thickness returns to the initial values in the fourth and sixth weeks of contact lens wearing. Peripheral corneal thickness was statistically related to the time of contact lens wearing (P < 0.01). A statistically significant difference was observed between the baseline and peripheral corneal thickness measurements in the second, fourth, and sixth week of contact lens wearing (P < 0.01).
Frequent-replacement contact lenses (ACUVUE) cause a small amount of corneal edema, which is higher in the periphery than in the center. Central corneal swelling disappears after 6 weeks of wearing, but in the periphery it remains stable throughout the period of observation.
评估频繁更换型隐形眼镜佩戴2周、4周和6周后角膜厚度的变化。
28例患者佩戴强生公司的ACUVUE隐形眼镜。在佩戴隐形眼镜前以及佩戴2周、4周和6周后测量中央和周边角膜厚度。
方差分析显示，隐形眼镜佩戴时间对中央角膜厚度无影响。在第二周有小幅增加后，中央角膜厚度在佩戴隐形眼镜的第四周和第六周恢复到初始值。周边角膜厚度与隐形眼镜佩戴时间有统计学关联（P < 0.01）。在佩戴隐形眼镜的第二周、第四周和第六周，基线与周边角膜厚度测量值之间存在统计学显著差异（P < 0.01）。
频繁更换型隐形眼镜（ACUVUE）会导致少量角膜水肿，周边的水肿程度高于中央。佩戴6周后中央角膜肿胀消失，但在周边在整个观察期内保持稳定。
