Vido I, Atay Z, Zobl H, Schmidt F W
Dtsch Med Wochenschr. 1975 Dec 19;100(51):2602-4. doi: 10.1055/s-0028-1106593.
Fine needle aspiration biopsy is generally a harmless method if contraindications are considered and provides sufficient tissue for cytological evaluation. The diagnostic value is very high: in 27 cases of metastatic tumours of the liver diagnosed by laparoscopy the diagnosis was confirmed in 26 cases and revised in one case. In a control group of 200 patients with various diffuse liver diseases or morphologically normal findings no false positive results were found. In no case were post-biopsy haemorrhage or other complications observed. Needle biopsy and cytological evaluation should be used with an increased frequency when a malignant tumour of the liver is suspected clinically. After primary localization of suspicious areas by ultrasound or scanning the pick-up rate is high. Laparoscopy with precisely aimed fine needle biopsy is the method for verifying the diagnosis in cases with cytologically negative results which is up to 100% accurate.
如果考虑到禁忌证，细针穿刺活检通常是一种无害的方法，并且能提供足够的组织用于细胞学评估。其诊断价值非常高：在通过腹腔镜检查诊断出的27例肝转移性肿瘤病例中，26例得到确诊，1例诊断被修正。在200例患有各种弥漫性肝病或形态学正常的对照组患者中，未发现假阳性结果。在任何情况下均未观察到活检后出血或其他并发症。当临床上怀疑有肝恶性肿瘤时，应增加针吸活检和细胞学评估的使用频率。通过超声或扫描对可疑区域进行初步定位后，采集率很高。对于细胞学检查结果为阴性的病例，采用精确瞄准的细针活检的腹腔镜检查是验证诊断的方法，其准确率高达100%。
