Xavier Lyndon C, Kern Karl B
Department of Medicine, Sarver Heart Center, University of Arizona, Tucson, Arizona 85724, USA.
Curr Opin Crit Care. 2003 Jun;9(3):218-21. doi: 10.1097/00075198-200306000-00008.
To examine the literature for new resuscitation science since the publication of the Guidelines 2000 for Cardiopulmonary Resuscitation and Emergency Cardiac Care.
The two and a half years since the publication of the Guidelines 2000 have seen the advent of a number of new and important resuscitation studies. Such studies highlight the importance of simplification of cardiopulmonary resuscitation techniques and guidelines, including the elimination of the layperson pulse check and the need for a simple form of basic life support cardiopulmonary resuscitation that decreases interruptions of chest compressions. Automatic external defibrillators, even in the hands of nontraditional first responders, are effective and safe. A second prospective, randomized clinical trial of amiodarone for refractory ventricular fibrillation has again shown positive results in improving survival to hospital admission. Finally, mild hypothermia appears to be the first effective therapy at decreasing central nervous system injury when administered after resuscitation.
In this report, we review these new studies and discuss how they corroborate or alter the published 2000 guidelines.
自《2000年心肺复苏和心脏急救指南》发布以来，对有关新复苏科学的文献进行研究。
自《2000年指南》发布后的两年半时间里，出现了许多新的重要复苏研究。这些研究强调了简化心肺复苏技术和指南的重要性，包括取消非专业人员的脉搏检查，以及需要一种简单的基本生命支持心肺复苏形式以减少胸外按压的中断。自动体外除颤器即使由非传统急救人员使用也是有效且安全的。第二项关于胺碘酮治疗难治性室颤的前瞻性随机临床试验再次显示出在提高入院生存率方面的积极结果。最后，轻度低温似乎是复苏后降低中枢神经系统损伤的首个有效疗法。
在本报告中，我们回顾了这些新研究，并讨论它们如何证实或改变已发布的2000年指南。
