Windahl Torgny, Andersson Swen-Olof
Department of Urology, Orebro University Hospital, Orebro, Sweden.
J Urol. 2003 Jun;169(6):2118-21. doi: 10.1097/01.ju.0000067361.81295.a2.
We evaluated local disease control, side effects and cause specific survival of penile carcinoma treated with laser therapy.
In a prospective study from 1986 to 2002 we included 67 men with a mean age of 60 years with newly diagnosed penile carcinoma. No patient was lost to followup.
At a median followup of 42 months (range 12 to 186) 59 patients were alive and 8 had died of penile carcinoma (2) and concurrent disease (6). Of the 13 patients (19%) with local recurrence during the study period 10 underwent repeat laser treatment successfully. Side effects were few but 5 patients (7%) had postoperative bleeding. Overall cosmetic and functional results were highly satisfactory.
The results of this study show that treating penile carcinoma with the combination of carbon dioxide and neodymium:YAG lasers can safely be done with highly satisfactory cosmetic results as well as good local tumor control.
我们评估了激光治疗阴茎癌的局部疾病控制、副作用及特定病因生存率。
在一项1986年至2002年的前瞻性研究中,我们纳入了67例平均年龄为60岁的新诊断阴茎癌男性患者。无患者失访。
中位随访42个月(范围12至186个月)时,59例患者存活,8例死于阴茎癌(2例)和并发疾病(6例)。在研究期间,13例(19%)出现局部复发的患者中,10例成功接受了重复激光治疗。副作用较少,但5例(7%)患者术后出血。总体美容和功能结果非常令人满意。
本研究结果表明,联合使用二氧化碳激光和钕:钇铝石榴石激光治疗阴茎癌可安全进行,美容效果非常令人满意,局部肿瘤控制良好。