Blatstein L M, Finkelstein L H
Department of Surgery, Osteopathic Medical Center of Philadelphia.
J Am Osteopath Assoc. 1990 Apr;90(4):338-44.
We describe our experience with six cases of squamous cell carcinoma of the penis treated with the carbon dioxide and neodymium yttrium aluminum garnet (Nd:YAG) lasers. One patient had carcinoma in situ. One patient had a T1 tumor. Two patients had T2 disease and two patients had T3 carcinoma of the penis when seen. The patients were followed up from 13 to 64 months. The patients with carcinoma in situ and T1 carcinoma of the penis were tumor-free at a mean follow-up of 45 months. One patient with T2 carcinoma apparently had a complete response to surgery; however, he was seen 56 months after the initial laser treatment with a new invasive penile tumor located at a different site that failed to respond to laser treatment and required a penectomy. Another man with T2 carcinoma as well as the two men with T3 carcinoma failed to respond to laser treatment and required a penectomy. It appears that laser surgery offers the potential for cure in patients with carcinoma of the penis with superficial involvement.
我们描述了6例阴茎鳞状细胞癌患者接受二氧化碳激光和钕钇铝石榴石（Nd:YAG）激光治疗的经验。1例患者为原位癌。1例患者为T1期肿瘤。2例患者为T2期疾病，2例患者初诊时为阴茎T3期癌。对患者进行了13至64个月的随访。原位癌和阴茎T1期癌患者在平均45个月的随访中无肿瘤。1例T2期癌患者对手术有明显的完全缓解；然而，在初次激光治疗56个月后，他被发现有一个新的浸润性阴茎肿瘤，位于不同部位，对激光治疗无反应，需要进行阴茎切除术。另1例T2期癌患者以及2例T3期癌患者对激光治疗无反应，需要进行阴茎切除术。看来激光手术为浅表浸润性阴茎癌患者提供了治愈的可能性。
