World Health Organ Tech Rep Ser. 2003;915:i-v, 1-26, back cover.
This report presents the recommendations of a WHO Expert Committee responsible for reviewing information on dependence-producing drugs to assess the need for their international control. The first part of the report contains a description of the procedure for the review of dependence-producing substances. This is followed by a critical review of five psychoactive substances (amfepramone, amineptine, buprenorphine, delta-9-tetrahydrocannabinol and tramadol). The report also discusses the substances that were pre-reviewed by the Committee, four of which (ketamine, zopiclone, butorphanol and khat) were recommended for critical review at a future meeting. The final section discusses the problems of the terminology used in reporting abuse-related adverse drug reactions and describes how confusion affects the reporting of adverse effects using the example of the selective serotonin reuptake inhibitors.
本报告介绍了世界卫生组织一个专家委员会的建议，该委员会负责审查有关致依赖性药物的信息，以评估对其进行国际管制的必要性。报告的第一部分介绍了审查致依赖性物质的程序。随后对五种精神活性物质（安非拉酮、阿密曲替林、丁丙诺啡、Δ⁹-四氢大麻酚和曲马多）进行了批判性审查。报告还讨论了委员会预先审查的物质，其中四种（氯胺酮、佐匹克隆、布托啡诺和巧茶）建议在未来会议上进行批判性审查。最后一部分讨论了报告与药物滥用相关的药物不良反应时所用术语的问题，并以选择性5-羟色胺再摄取抑制剂为例描述了混淆如何影响不良反应的报告。
