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[支气管哮喘患者的脂质过氧化与抗氧化防御系统酶]

[Lipid peroxidation and enzymes of the antioxidant defense system in patients with bronchial asthma].

作者信息

Abdullaev S F, Inoiatov F Sh

出版信息

Lik Sprava. 2003(2):28-31.

Abstract

In 71 patient with bronchial asthma (BA), lipid peroxidation (LPO) was studied together with the condition of the antioxidant system (AOS) as related to the degree of severity of the illness, with results evaluated of conventional therapy versus complex treatment involving the use of cytochrome C. Established in the above series was intensification of LPO in the presence of inhibition of activity of SOD enzymes and catalase, their degree dependent on severity of the condition. Unlike basic therapy, employment of cytochrome C has been found to be associated with a more complete restoration of balance in the LPO/AOS system, especially so in steroid-independent form of BA.

摘要

对71例支气管哮喘(BA)患者,研究了脂质过氧化(LPO)以及抗氧化系统(AOS)状况与疾病严重程度的关系,并评估了传统疗法与使用细胞色素C的综合治疗的效果。在上述病例系列中发现,超氧化物歧化酶(SOD)和过氧化氢酶活性受到抑制时,LPO增强,其程度取决于病情严重程度。与基础治疗不同,使用细胞色素C已被发现与LPO/AOS系统平衡的更完全恢复相关,在非依赖类固醇型BA中尤其如此。

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