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[支气管哮喘和喘息性支气管炎患者在分级体力负荷下的脂质过氧化和抗氧化系统]

[Lipid peroxidation and the antioxidant system in patients with bronchial asthma and asthmatic bronchitis subjected to graded physical load].

作者信息

Amatuni V G, Safarian M D

出版信息

Ter Arkh. 1986;58(4):23-5.

PMID:3715752
Abstract

A study was made of lipid peroxidation and the antioxidant system in patients with bronchial asthma (BA) and chronic asthmatic bronchitis (CAB) before and after muscular exercise. Physical exercise in BA patients was accompanied by an increase in the amount of hydroperoxides and a raised activity of superoxide dismutase (SOD) and a drop of peroxidase and catalase activity. Peroxidase and SOD activity did not increase in CAB patients in whom muscular exercise caused no bronchospastic syndrome in the presence of an increase in the amount of hydroperoxides.

摘要

对支气管哮喘(BA)和慢性哮喘性支气管炎(CAB)患者在肌肉运动前后的脂质过氧化和抗氧化系统进行了研究。BA患者进行体育锻炼时,氢过氧化物量增加,超氧化物歧化酶(SOD)活性升高,而过氧化物酶和过氧化氢酶活性下降。在CAB患者中,肌肉运动在氢过氧化物量增加的情况下未引起支气管痉挛综合征,过氧化物酶和SOD活性未增加。

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