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在一项大型实验室间调查中对所建立的成分目标值可靠性的研究。

Studies of the reliability of constituent target values established in a large inter-laboratory survey.

作者信息

Grannis G F

出版信息

Clin Chem. 1976 Jul;22(7):1027-36.

PMID:1277500
Abstract

Lyophilized serum specimens were manufactured in such a way that fixed quantitative interspecimen relationships were established. The specimens were analyzed for about twenty constituents by several thousand laboratories in 1971, 1972, and 1973. Most of the consensus mean values derived from these analyses were found to relect accurately the relationships established in the manufacture of the specimens. In addition, analyses of some of the specimens for calcium by the National Bureau of Standards confirmed the relationships. I conclude that the consensus mean values derived for most constituents are reproducible and any biases that may be present are consistent from survey to survey.

摘要

冻干血清标本的制作方式能够建立固定的标本间定量关系。1971年、1972年和1973年,数千个实验室对这些标本进行了约二十种成分的分析。从这些分析得出的大多数共识均值被发现准确反映了标本制作过程中建立的关系。此外,国家标准局对部分标本进行的钙分析也证实了这些关系。我得出结论,大多数成分的共识均值是可重现的,并且每次调查中可能存在的任何偏差都是一致的。

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