Moreno-Arias G A, Conill C, Sola-Casas M A, Mascaro-Galy J M, Grimalt R
Department of Dermatology, Hospital Clinic, University of Barcelona, Villaroel 170, 08036 Barcelona, Spain.
J Dermatolog Treat. 2003 Jun;14(2):119-23. doi: 10.1080/09546630305537.
Radiotherapy as a first-choice treatment for in situ extramammary Paget disease has been successfully used.
To review the most relevant aspects of radiotherapy as first-choice treatment in selected cases of in situ extramammary Paget disease of the vulva.
Two Caucasian females aged 76 and 92 years with in situ extramammary Paget disease localized in the genital region were treated by means of ortovoltage X-rays: 100 kV, 8 mA, 1.7 mm Al filter, field size of 12-cm cone, and source skin distance of 30 cm. Both patients received 40 Gy, 200 cGy per fraction, five fractions per week.
Complete regression of in situ extramammary Paget disease was observed in both patients after radical radiation therapy and neither local recurrences nor internal malignancies were detected.
Radiotherapy is a curative treatment in selected cases of in situ extramammary Paget disease affecting the vulva.
放射治疗作为原位乳腺外佩吉特病的首选治疗方法已成功应用。
回顾放射治疗作为外阴原位乳腺外佩吉特病特定病例首选治疗方法的最相关方面。
两名分别为76岁和92岁的白种女性，患有局限于生殖器区域的原位乳腺外佩吉特病，采用正交电压X射线进行治疗：100 kV，8 mA，1.7 mm铝滤过器，12厘米圆锥野大小，源皮距30厘米。两名患者均接受40 Gy，每次分割剂量200 cGy，每周五次分割。
根治性放射治疗后，两名患者的原位乳腺外佩吉特病均完全消退，未检测到局部复发或内部恶性肿瘤。
放射治疗是治疗外阴原位乳腺外佩吉特病特定病例的一种治愈性方法。
