[蟾酥β-环糊精包合物的制备研究]
[Study on the preparation of venenum bufonis beta-cyclodextrin inclusion complexes].
作者信息
Guo Tao, Song Hong-tao, Zhao Ming-hong, Zhang Ru-hua, Li Xian
机构信息
Shenyang Military General Hospital, Shenyang 110016, Liaoning, China.
出版信息
Zhongguo Zhong Yao Za Zhi. 2002 Nov;27(11):835-7.
OBJECTIVE
To study the preparation of Venenum Bufonis beta-cyclodextrin inclusion complexes.
METHOD
An optimal condition was established by the uniform design. Under the optimal conditions the Venenum Bufonis beta-cyclodextrin inclusion complexes were prepared with 5 different methods.
RESULT
The ball grinding method was superior to other four methods. The bufadienolide inclusion rate of Venenum Bufonis beta-cyclodextrin prepared with ball grinding method was 85.42%.
CONCLUSION
Ball grinding method is the best method for the preparation of Venenum Bufonis beta-cyclodextrin inclusion complexes.
目的
研究蟾酥β-环糊精包合物的制备。
方法
采用均匀设计法确定最佳条件。在最佳条件下，用5种不同方法制备蟾酥β-环糊精包合物。
结果
球磨法优于其他4种方法。用球磨法制备的蟾酥β-环糊精中蟾毒内酯的包合率为85.42%。
结论
球磨法是制备蟾酥β-环糊精包合物的最佳方法。
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