Merguerian Paul A
Department of Pediatric Urology, Children's Hospital Central California, 9300 Valley Children's Place, Madera, CA 93638, USA.
Curr Opin Oncol. 2003 May;15(3):222-6. doi: 10.1097/00001622-200305000-00008.
Advances continue to be made in the evaluation and treatment of genitourinary tumors in children. Continued research on the cellular, molecular, and genetic process in tumorigenesis is rapidly evolving. We review the 2002 literature on pediatric genitourinary tumors. Molecular and cellular biology research continues to identify markers that may predict a worse prognosis. This identification will allow a more tailored approach with intensified treatment of aggressive tumors.
儿童泌尿生殖系统肿瘤的评估和治疗不断取得进展。对肿瘤发生过程中的细胞、分子和遗传过程的持续研究正在迅速发展。我们回顾了2002年关于儿童泌尿生殖系统肿瘤的文献。分子和细胞生物学研究继续识别可能预示预后较差的标志物。这种识别将使针对侵袭性肿瘤的治疗方法更加个体化和强化。
