Egenvall A, Hansson K, Säteri H, Lord P F, Jönsson L
Department of Ruminant Medicine and Veterinary Epidemiology, Swedish University of Agricultural Sciences, Uppsala, Sweden.
J Small Anim Pract. 2003 May;44(5):209-17. doi: 10.1111/j.1748-5827.2003.tb00145.x.
A syndrome of acute dyspnoea after hunting in 16 Swedish hunting dogs is characterised. Radiographic pulmonary infiltrates interpreted as pulmonary oedema were found in the acute stage. In 12 dogs, the infiltrates regressed after five to 14 days. Subendocardial necrosis and pulmonary oedema were found at postmortem examination in four other dogs with acute and recurrent dyspnoea after hunting, and myocardial fibrosis in a further three dogs with a history of recurrent dyspnoea after hunting; none of these pathological changes was seen in dogs which had no previous history of dyspnoea after hunting. A pathogenetic mechanism is proposed whereby high catecholamine levels, present during hunting due to the stress of excitement and exercise, cause acute cardiac and pulmonary lesions in some susceptible dogs, similar to neurogenic or postictal pulmonary oedema.
对16只瑞典猎犬狩猎后出现的急性呼吸困难综合征进行了特征描述。在急性期发现胸部X光片上的肺部浸润影,被解释为肺水肿。12只犬的浸润影在5至14天后消退。在另外4只狩猎后出现急性和反复性呼吸困难的犬尸检时发现心内膜下坏死和肺水肿,另有3只曾有狩猎后反复性呼吸困难病史的犬发现心肌纤维化;在没有狩猎后呼吸困难病史的犬中未见到这些病理变化。提出了一种发病机制,即由于兴奋和运动的应激,狩猎期间出现的高儿茶酚胺水平在一些易感犬中导致急性心脏和肺部病变,类似于神经源性或癫痫后肺水肿。